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2015). These scientific tests, taken together, recommend that, Despite the fact that a direct activation of GPR55 or PPAR?? takes place, PEA can create its anti?inflammatory action while in the intestine also through indirect activation of CB1 and CB2 receptors, most likely because of the ability of the compound to potentiate the motion of endocann
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Abstract Long-term pain is An important supply of morbidity for which you will find limited helpful treatment options. Palmitoylethanolamide (PEA), a naturally taking place fatty acid amide, has demonstrated utility in the treatment of neuropathic and inflammatory suffering. Rising stories have supported a achievable part for its use in the treatme